Opportunity Information: Apply for RFA CA 17 021
This funding opportunity (RFA-CA-17-021) is a National Institutes of Health (NIH), National Cancer Institute (NCI) call for revision applications to existing NCI-supported P01 program project grants. The main purpose is to let current P01 awardees add a new, additional research project to their funded program that specifically tackles one of NCI's "Provocative Questions" (PQs). These PQs are a set of high-priority, challenge-style research questions NCI published in the companion announcements RFA-CA-17-017 (aimed at R01-level projects) and RFA-CA-17-018 (aimed at R21-level projects). In practical terms, NCI is using this mechanism to inject PQ-driven work into already-established, multi-project P01 programs, rather than funding only brand-new standalone grants.
The revision is expected to be centered on one of the 12 PQs and must be presented as a new research project that expands the scope of the parent P01 while still fitting tightly within the overall theme and integration of the program project. That integration point is important: this is not meant to be an unrelated add-on, but a project that complements the existing P01 structure and strengthens the coordinated, multi-project approach that defines P01 awards. The FOA also signals that NCI is interested not only in studies that directly answer a PQ, but also in work that validates outcomes from PQ research, and in efforts that help adopt, translate, disseminate, or otherwise move PQ-derived findings into broader cancer research practice or clinical care. In other words, the announcement leaves room for projects that either generate new PQ-focused discoveries or solidify and spread PQ-related results that can make a real difference.
The opportunity is categorized as a discretionary grant program in the education and health funding activity area and is associated with multiple CFDA numbers (93.393, 93.394, 93.395, 93.396, 93.399), reflecting NCI's broader research portfolio. The award ceiling listed is $150,000, which suggests a capped budget level for the revision component (as opposed to the full parent P01 budget). The original closing date for applications was January 23, 2018, and the opportunity record was created March 13, 2017.
Eligibility is broad and includes many types of U.S.-based organizations and government entities that commonly participate in NIH funding. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education under those particular lines); for-profit organizations (other than small businesses); and small businesses. The FOA also highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, tribal governments other than federally recognized ones, and U.S. territories or possessions.
Foreign participation is handled in a very specific way. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply as the applicant organization. Likewise, foreign institutions are not eligible to apply. However, foreign components are allowed as defined by the NIH Grants Policy Statement, meaning a U.S.-based applicant may include certain foreign project components when they are scientifically justified and meet NIH policy requirements. This structure is typical of NIH opportunities that want to keep the applicant and primary administrative control in the United States while still allowing international collaboration where it strengthens the science.
Overall, this FOA is best understood as a targeted supplement-like pathway for existing NCI P01 programs to take on a new PQ-focused project, using the revision mechanism to broaden the parent program in a controlled, theme-consistent way. It is aimed at accelerating progress on NCI's most pressing cancer research challenges by leveraging established P01 teams and infrastructure, while still requiring that the added work be a true expansion of scope that remains integrated with the parent program's goals.Apply for RFA CA 17 021
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Revision Applications to National Cancer Institute (NCI)-supported P01 Awards to Include Research on the NCI's Provocative Questions (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.396, 93.399.
- This funding opportunity was created on 2017-03-13.
- Applicants must submit their applications by 2018-01-23. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
FAQs: NIH/NCI RFA-CA-17-021 (P01 Revision Applications for Provocative Questions)
What is RFA-CA-17-021?
RFA-CA-17-021 is a National Institutes of Health (NIH), National Cancer Institute (NCI) funding opportunity announcement that calls for revision applications to existing NCI-supported P01 Program Project Grants. The revision is used to add a new, additional research project to an active P01 program.
What is the main goal of this funding opportunity?
The main goal is to allow current NCI P01 awardees to expand their funded program by adding a new project that specifically addresses one of NCI's "Provocative Questions" (PQs). NCI is using this mechanism to bring PQ-driven work into established multi-project P01 programs rather than funding only brand-new standalone awards.
Who can apply for this opportunity?
This opportunity is intended for existing NCI-supported P01 Program Project Grant awardees submitting a revision application to their parent P01. The revision must add a new research project that expands the scope of the parent program while remaining integrated with the P01's overall theme.
Is this funding for brand-new grants, or only for revisions?
This is for revision applications to existing NCI-supported P01 awards. It is not described as a mechanism for new standalone grants; it is specifically a pathway to add a new project to an already-funded P01 program.
What are NCI "Provocative Questions" (PQs) in this context?
PQs are a set of high-priority, challenge-style research questions published by NCI. Under this opportunity, the revision is expected to be centered on one of the 12 PQs.
Where do the Provocative Questions come from?
The PQs referenced here are described as being published in companion announcements RFA-CA-17-017 (aimed at R01-level projects) and RFA-CA-17-018 (aimed at R21-level projects). This revision opportunity is designed to incorporate PQ-related work into existing P01 programs.
How many Provocative Questions are covered by this FOA?
The revision is expected to be centered on one of 12 Provocative Questions.
What exactly must be added to the parent P01?
The revision must be presented as a new, additional research project that expands the scope of the parent P01 while fitting tightly within the overall theme and integration of the program project.
Does the added project have to match the existing P01 theme?
Yes. The FOA emphasizes integration: the new project is not meant to be an unrelated add-on. It should complement the existing P01 structure and strengthen the coordinated, multi-project approach that defines P01 awards.
Can the new project be somewhat independent, or does it need to be integrated?
It needs to be integrated. The announcement highlights that integration within the P01 is important and that the added work should strengthen the coordinated, multi-project approach rather than functioning as an unrelated stand-alone effort.
Does the new project have to directly answer a Provocative Question?
The FOA indicates interest in studies that directly answer a PQ, but it also signals interest in related work that validates outcomes from PQ research and in efforts that help adopt, translate, disseminate, or otherwise move PQ-derived findings into broader cancer research practice or clinical care.
Is translation, dissemination, or adoption work considered responsive?
Yes. The FOA leaves room for projects that help adopt, translate, disseminate, or otherwise move PQ-derived findings into broader cancer research practice or clinical care, in addition to projects that generate new PQ-focused discoveries.
What is the maximum award amount for this opportunity?
The award ceiling listed is $150,000. This appears to be a capped budget level for the revision component, not the total budget of the parent P01.
How is this opportunity categorized?
It is categorized as a discretionary grant program in the education and health funding activity area.
Which CFDA numbers are associated with this FOA?
The opportunity is associated with multiple CFDA numbers: 93.393, 93.394, 93.395, 93.396, and 93.399.
When was the opportunity record created?
The opportunity record was created on March 13, 2017.
What was the closing date for applications?
The original closing date listed for applications was January 23, 2018.
What types of organizations are eligible to apply (in general NIH terms)?
Eligibility is described as broad and includes many U.S.-based organizations and government entities commonly involved in NIH funding. Examples listed include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (under the lines described); for-profit organizations (other than small businesses); and small businesses.
Are U.S. minority-serving or special-designation institutions mentioned as eligible?
Yes. The FOA highlights additional eligible applicant types including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based and community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly highlighted among eligible applicant types.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among the eligible applicant types highlighted in the FOA description provided.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are listed among the additional eligible applicant types.
Can a foreign (non-U.S.) institution apply as the applicant organization?
No. Non-domestic (non-U.S.) entities are not eligible to apply as the applicant organization, and foreign institutions are not eligible to apply.
Can a U.S. applicant include foreign components in the proposed work?
Yes. While foreign institutions cannot be the applicant, foreign components are allowed as defined by the NIH Grants Policy Statement, when scientifically justified and consistent with NIH policy requirements.
Are non-domestic components of U.S. organizations allowed?
Non-domestic components of U.S. organizations are not eligible to apply as the applicant organization. However, foreign components may be included under NIH policy when scientifically justified.
What is the overall intent of using the revision mechanism for PQ projects?
The intent is to accelerate progress on NCI's pressing cancer research challenges by leveraging established P01 teams and infrastructure, while requiring that the added work be a true expansion of scope and remain integrated with the parent program's goals.
Browse more opportunities from the same category: Education, Health
Next opportunity: Modeling of Infectious Disease Agent Study Research Projects (R01)
Previous opportunity: Strengthening the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum through Behavioral, Social, and Implementation Science (R01)
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA CA 17 021
Applicants also applied for:
Applicants who have applied for this opportunity (RFA CA 17 021) also looked into and applied for these:
| Funding Opportunity |
|---|
| Revision Applications to National Cancer Institute (NCI)-supported P50 Awards to Include Research on the NCI's Provocative Questions (P50) Apply for RFA CA 17 022 Funding Number: RFA CA 17 022 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revision Applications to NCI-supported R01 Awards to Include Research on the NCI's Provocative Questions (R01) Apply for RFA CA 17 019 Funding Number: RFA CA 17 019 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Supplements for Validating the Use of Automated Sources of Residential Histories in Cancer Epidemiology Cohorts (Admin Supp) Apply for PA 17 222 Funding Number: PA 17 222 Agency: National Institutes of Health Category: Education, Health Funding Amount: $125,000 |
| Research Supplements to Promote Sharing Data in Cancer Epidemiology Studies (Admin Supp) Apply for PA 17 224 Funding Number: PA 17 224 Agency: National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| Supplement Opportunity to Support Population-Based Research Studies of Rare Cancers (Admin Supp) Apply for PA 17 223 Funding Number: PA 17 223 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Advancing the Science of Geriatric Palliative Care (R01) Apply for PA 17 225 Funding Number: PA 17 225 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Advancing the Science of Geriatric Palliative Care (R21) Apply for PA 17 226 Funding Number: PA 17 226 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01) Apply for PAR 17 233 Funding Number: PAR 17 233 Agency: National Institutes of Health Category: Education, Health Funding Amount: $1,250,000 |
| Mechanisms and Consequences of Sleep Disparities in the U.S. (R21) Apply for PAR 17 235 Funding Number: PAR 17 235 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Innovative Research in Cancer Nanotechnology (IRCN) (R01) Apply for PAR 17 240 Funding Number: PAR 17 240 Agency: National Institutes of Health Category: Education, Health Funding Amount: $450,000 |
| Mechanisms and Consequences of Sleep Disparities in the U.S. (R01) Apply for PAR 17 234 Funding Number: PAR 17 234 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Fostering Research Training and Education Programs for Native American Students at NCI-designated Cancer Centers (Admin Supp) Apply for PA 17 241 Funding Number: PA 17 241 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Avenir Award Program for Research on Substance Abuse and HIV/AIDS (DP2) Apply for RFA DA 18 004 Funding Number: RFA DA 18 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21) Apply for PA 17 243 Funding Number: PA 17 243 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R01) Apply for PA 17 239 Funding Number: PA 17 239 Agency: National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Activities to Promote Research Collaborations on Immune-Related Adverse Events (APRC-irAEs) Associated with Cancer Immunotherapy (Admin Supp) Apply for PA 17 248 Funding Number: PA 17 248 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Collaborative Research Projects to Enhance Applicability of Mammalian Models for Translational Research (Collaborative R01) Apply for PAR 17 244 Funding Number: PAR 17 244 Agency: National Institutes of Health Category: Education, Health Funding Amount: $450,000 |
| Extracellular Vesicles and Substance Use Disorders (R21) Apply for PAR 17 242 Funding Number: PAR 17 242 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01) Apply for PAR 17 245 Funding Number: PAR 17 245 Agency: National Institutes of Health Category: Education, Health Funding Amount: $450,000 |
| Extracellular Vesicles and Substance Use Disorders (R01) Apply for PAR 17 250 Funding Number: PAR 17 250 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA CA 17 021", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.