Modeling of Infectious Disease Agent Study Research Projects (R01) | PAR 17 267

Opportunity Information: Apply for PAR 17 267

Modeling of Infectious Disease Agent Study Research Projects (R01) (Funding Opportunity Number PAR 17 267) is a National Institutes of Health discretionary grant program designed to fund innovative research that improves how infectious diseases are modeled, predicted, and managed. The central aim is to support the development and application of computational tools and methods that can capture key dynamics of infectious agents and their hosts, including how pathogens interact with immune systems, how diseases spread through populations, and how outbreaks might be anticipated and controlled. A major emphasis is on producing models that are not just academically interesting, but genuinely useful to end users such as biomedical researchers, public health professionals, and policymakers who need better ways to understand risk, plan interventions, and evaluate response options.

The projects supported under this FOA are expected to strengthen real-world preparedness and response capabilities by providing better resources, knowledge, and modeling tools. That includes efforts that help communities and public health systems prepare for, identify, detect, control, and prevent infectious disease threats. The scope explicitly covers diseases caused by naturally occurring pathogens as well as those that might be intentionally released, making the program relevant to biodefense priorities in addition to routine public health needs. In practical terms, the FOA encourages research that can translate into improved decision support, such as predictive modeling frameworks, simulations of intervention strategies, scenario testing for outbreak response, and computational approaches that clarify transmission patterns or host-pathogen mechanisms.

The award uses the NIH R01 mechanism, meaning it is structured to support substantial, investigator-driven research projects rather than small pilot efforts. The funding instrument type is a grant, and the activity category is health, with CFDA numbers listed as 93.855, 93.856, and 93.859. While the source data does not specify an award ceiling or the anticipated number of awards, the R01 format generally signals support for well-developed research plans with clear aims, strong methodological rigor, and meaningful potential impact.

Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (including those other than federally recognized tribal governments); public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions when noted); for-profit organizations other than small businesses; and small businesses. The FOA also highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISI); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); eligible federal government agencies; faith-based or community-based organizations; U.S. territories or possessions; regional organizations; tribal governments other than federally recognized; and foreign organizations (non-U.S. entities). This wide eligibility is consistent with the program’s goal of expanding modeling capacity and encouraging participation from diverse institutions and communities, including those positioned to address region-specific infectious disease risks.

Key administrative details in the provided record include an original closing date of May 7, 2019, and a creation date of May 5, 2017. Overall, the opportunity is best understood as NIH support for computational and mathematical modeling research that can improve outbreak understanding and response, strengthen public health readiness, and enhance biodefense-relevant capabilities by turning data and biological insight into practical predictive and decision-support tools.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Modeling of Infectious Disease Agent Study Research Projects (R01)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855, 93.856, 93.859.
• This funding opportunity was created on 2017-05-05.
• Applicants must submit their applications by 2019-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 17 267

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