Opportunity Information: Apply for PAR 21 275
The National Institutes of Health (NIH) funding opportunity titled "The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)" (Opportunity Number PAR-21-275) is a discretionary grant program designed to support innovative, population-based research focused on how work and occupation shape health outcomes in the United States. The central aim is to help researchers identify and explain the pathways and mechanisms through which working conditions, occupational roles, and employment-related factors contribute to differences in health status and health outcomes, especially among populations experiencing health and/or health care disparities. In practical terms, NIH is looking for studies that treat work not just as an individual experience but as a major social determinant of health that can drive unequal exposure to risks, unequal access to protective resources, and unequal downstream health consequences across communities.
This FOA uses the R01 research project grant mechanism and allows clinical trials, but does not require them (clinical trials are optional). The emphasis on "population-based" research suggests a focus on studies that can generalize beyond a single workplace or small convenience sample, including research that examines patterns across industries, geographic areas, or demographic groups, and that can connect occupational exposures to broader structural and social factors. Projects supported under this announcement are expected to contribute to a clearer understanding of how work-related factors (such as job type, job security, wages, scheduling, benefits, physical and psychosocial hazards, discrimination at work, labor policies, and access to protections) interact with social and economic conditions to produce or sustain health disparities.
Eligibility is broad and includes many types of U.S.-based organizations and governmental units. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); public housing authorities and Indian housing authorities; Native American tribal organizations (other than federally recognized tribal governments); nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other entities that meet NIH eligibility rules. The FOA also explicitly highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; regional organizations; eligible federal agencies; Indian/Native American Tribal Governments (other than federally recognized); and U.S. territories or possessions. This wide applicant pool signals an interest in encouraging research capacity across many kinds of institutions, including those closely connected to communities most affected by work-related inequities.
At the same time, the opportunity places firm limits on foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components as defined by the NIH Grants Policy Statement are not allowed. In other words, the applicant organization and the work funded under the award need to be entirely domestic in NIH terms.
The opportunity is categorized under Education, Environment, and Health, reflecting the cross-cutting nature of occupational determinants of health. It lists multiple CFDA numbers (93.113, 93.242, 93.279, 93.307, 93.313, 93.393, 93.396, 93.399, 93.866), indicating that multiple NIH Institutes or Centers may be participating or that the research scope aligns with several NIH program areas. The FOA was created on 2021-06-25, and the original closing date is listed as 2024-09-07. The award ceiling and expected number of awards are not specified in the provided data, which typically means applicants should rely on the full FOA and NIH institute guidance to understand budget expectations, project period norms, and likely funding levels.
Overall, this grant opportunity supports rigorous research that clarifies how employment and occupational conditions contribute to unequal health outcomes in the U.S., with the broader goal of strengthening the evidence base needed to understand and ultimately reduce health disparities linked to the world of work.Apply for PAR 21 275
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.279, 93.307, 93.313, 93.393, 93.396, 93.399, 93.866.
- This funding opportunity was created on 2021-06-25.
- Applicants must submit their applications by 2024-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants who have applied for this opportunity (PAR 21 275) also looked into and applied for these:
| Funding Opportunity |
|---|
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH)) Apply for PAR 21 273 Funding Number: PAR 21 273 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed) Apply for PAR 21 252 Funding Number: PAR 21 252 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Emerging Global Leader Award (K43 Independent Clinical Trial Required) Apply for PAR 21 251 Funding Number: PAR 21 251 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) (R01 Clinical Trial Optional) Apply for RFA ES 21 007 Funding Number: RFA ES 21 007 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $475,000 |
| Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed) Apply for PAR 22 072 Funding Number: PAR 22 072 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Emergency Award: Rapid Acceleration of Diagnostics Tribal Data Repository (RADx TDR) (U24 Clinical Trial Not Allowed) Apply for RFA OD 22 011 Funding Number: RFA OD 22 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,000,000 |
| CCRP Initiative: Countermeasures Against Chemical Threats (CounterACT) Therapeutics Discovery and Early-Stage Development (UG3/UH3 Clinical Trial Not Allowed) Apply for PAR 22 209 Funding Number: PAR 22 209 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Multi-Omics for Health and Disease - Disease Study Sites (U01 Clinical Trial Optional) Apply for RFA HG 22 008 Funding Number: RFA HG 22 008 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $500,000 |
| Multi-Omics for Health and Disease - Data Analysis and Coordination Center (U01 Clinical Trial Not Allowed) Apply for RFA HG 22 010 Funding Number: RFA HG 22 010 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $950,000 |
| Multi-Omics for Health and Disease - 'Omics Production Centers (U01 Clinical Trial Not Allowed) Apply for RFA HG 22 009 Funding Number: RFA HG 22 009 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,700,000 |
| The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Apply for RFA OD 22 028 Funding Number: RFA OD 22 028 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R01 Clinical Trial Optional) Apply for PAR 23 042 Funding Number: PAR 23 042 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Genomic Community Resources (U24 Clinical Trial Not Allowed) Apply for PAR 23 085 Funding Number: PAR 23 085 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Data Repository (U24 - Clinical Trials Not Allowed) Apply for PAR 23 079 Funding Number: PAR 23 079 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed) Apply for PAR 23 078 Funding Number: PAR 23 078 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Apply for RFA ES 23 004 Funding Number: RFA ES 23 004 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed) Apply for PAR 23 109 Funding Number: PAR 23 109 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Translational Exploratory/Developmental Research Projects (R21 Clinical Trial Not Allowed) Apply for PAR 23 139 Funding Number: PAR 23 139 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $275,000 |
| Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) Apply for RFA ES 23 001 Funding Number: RFA ES 23 001 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $2,000,000 |
| STrengthening Research Opportunities for NIH Grants (STRONG): Structured Institutional Needs Assessment and Action Plan Development for Resource Limited Institutions (RLIs) (UC2 - Clinical Trial Not Allowed) Apply for PAR 23 144 Funding Number: PAR 23 144 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $250,000 |
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