Opportunity Information: Apply for RFA DA 24 012
Substance Use Prevention Effectiveness Research Among Youth and Families in the Child Welfare System (R01 Clinical Trial Required) is a National Institutes of Health (NIH) funding opportunity (RFA-DA-24-012; CFDA 93.279) that supports effectiveness research testing real-world interventions or service approaches intended to prevent opioid misuse and opioid use disorder. The focus is explicitly on people connected to the child welfare system: youth, caregivers, foster parents, and families. The central idea is to build a stronger, practice-ready evidence base for prevention programs that can be delivered within child welfare settings or accessed through child welfare referrals, with the long-term aim of reducing both immediate and intergenerational substance use risk in families.
A key feature of the announcement is its broad definition of child welfare involvement. Projects can target families who are at risk of entering the child welfare system, those currently receiving child welfare services, and those who have already exited the system. This wider lens is meant to reflect how prevention needs often begin before formal system entry and can remain important after a case closes, especially for adolescents transitioning to adulthood and for caregivers navigating instability, trauma, or prior substance exposure in the household.
Because this is an R01 clinical trial required opportunity, applicants are expected to conduct rigorous, outcome-focused effectiveness studies in real-world conditions rather than only tightly controlled efficacy studies. In practice, that usually means testing interventions as they would actually be implemented in community and public service environments, accounting for typical staffing, caseload pressures, service constraints, and the complexities of working with families involved in child welfare. The interventions or services under study should be prevention-oriented and specifically aligned with reducing opioid misuse risk or preventing opioid use disorder among the targeted populations.
Eligible applicants span a wide range of domestic organizations and government entities. Public sector applicants can include state, county, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. Higher education institutions are eligible, including public and state-controlled institutions as well as private institutions. Tribal eligibility includes federally recognized Native American tribal governments and Native American tribal organizations that are not federally recognized, along with tribally controlled colleges and universities (TCCUs). Nonprofit organizations are eligible whether or not they hold 501(c)(3) status, as are for-profit organizations (other than small businesses) and small businesses. The opportunity also highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
Foreign participation is restricted in the usual NIH way for many opportunities: non-U.S. entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are not eligible. However, foreign components are allowed as defined in the NIH Grants Policy Statement, meaning a U.S.-based applicant may include certain well-justified international elements (for example, specific expertise, analytic capacity, or other components) if they meet NIH policy requirements and are appropriate to the project.
The posted administrative details indicate the opportunity is a discretionary grant with an award ceiling listed at $600,000. The original closing date shown is 2023-03-15, and the record creation date is 2022-12-16. Overall, the grant is aimed at generating actionable evidence about what prevention approaches actually work for opioid-related outcomes in child welfare-connected populations, with an emphasis on interventions that can be implemented in, embedded within, or linked through the child welfare system to reduce opioid misuse risk across youth and families.Apply for RFA DA 24 012
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Substance Use Prevention Effectiveness Research Among Youth and Families in the Child Welfare System (R01 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
- This funding opportunity was created on 2022-12-16.
- Applicants must submit their applications by 2023-03-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled Substance Use Prevention Effectiveness Research Among Youth and Families in the Child Welfare System (R01 Clinical Trial Required).
Which federal agency is sponsoring this grant?
This is a National Institutes of Health (NIH) funding opportunity.
What is the funding opportunity number (RFA) and CFDA listing?
The opportunity is identified as RFA-DA-24-012, and it lists CFDA 93.279.
What type of grant mechanism is this?
This opportunity is an R01 and is explicitly labeled Clinical Trial Required.
What is the overall purpose of this grant?
The goal is to support effectiveness research that tests real-world interventions or service approaches intended to prevent opioid misuse and opioid use disorder, specifically among people connected to the child welfare system.
What population(s) does this opportunity focus on?
The focus is explicitly on people connected to the child welfare system, including youth, caregivers, foster parents, and families.
What does the grant mean by "child welfare involvement"?
The announcement uses a broad definition. Projects may target families who are at risk of entering the child welfare system, those currently receiving services, and those who have already exited the system.
Can projects focus on families before they formally enter the child welfare system?
Yes. The opportunity allows projects targeting families at risk of entering the child welfare system.
Can projects focus on families after they have exited the child welfare system?
Yes. The opportunity allows projects targeting families who have already exited the system, reflecting that prevention needs can continue after a case closes.
What kinds of interventions or services are expected to be studied?
Interventions or service approaches should be prevention-oriented and specifically aligned with reducing opioid misuse risk or preventing opioid use disorder in the targeted child welfare-connected populations.
Is the emphasis on efficacy studies or effectiveness studies?
The emphasis is on effectiveness studies conducted under real-world conditions, rather than only tightly controlled efficacy research.
What does "real-world conditions" imply for study design and implementation?
It implies testing interventions as they would be implemented in community and public service environments, accounting for typical realities such as staffing, caseload pressures, service constraints, and the complexities of working with families involved in child welfare.
Where should interventions be delivered or accessed?
The opportunity prioritizes prevention programs that can be delivered within child welfare settings or accessed through child welfare referrals.
What long-term outcomes is this grant trying to influence?
The long-term aim is to reduce both immediate and intergenerational substance use risk in families connected to the child welfare system.
Who is eligible to apply?
Eligible applicants include a broad set of U.S.-based organizations and government entities, including public sector entities, higher education institutions, tribal entities, nonprofits, and for-profit organizations (including small businesses).
Which government entities are eligible applicants?
Eligible public sector applicants can include state, county, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are colleges and universities eligible?
Yes. Eligible institutions include public and state-controlled institutions and private institutions of higher education.
Are tribal governments and tribal organizations eligible?
Yes. Eligibility includes federally recognized Native American tribal governments and Native American tribal organizations that are not federally recognized. Tribally controlled colleges and universities (TCCUs) are also listed as eligible.
Are nonprofit organizations eligible to apply?
Yes. Nonprofits are eligible with or without 501(c)(3) status.
Are for-profit organizations eligible to apply?
Yes. For-profit organizations are eligible, including small businesses, with the note that the opportunity specifies for-profit organizations (other than small businesses) and small businesses as eligible types.
Are faith-based or community-based organizations eligible?
Yes. The opportunity highlights faith-based or community-based organizations among eligible applicant types.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The opportunity highlights eligibility for institutions such as HBCUs, Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs).
Are U.S. territories or possessions eligible?
Yes. The opportunity includes U.S. territories or possessions among eligible applicant types.
Are foreign (non-U.S.) organizations eligible to apply as the applicant organization?
No. Non-U.S. entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization for this opportunity.
Can a U.S. applicant include non-domestic components?
No. Non-domestic components of U.S. organizations are stated as not eligible.
Are any international or foreign components allowed in the project?
Yes, limited foreign involvement may be possible. The opportunity indicates that foreign components are allowed as defined in the NIH Grants Policy Statement, meaning a U.S.-based applicant may include well-justified international elements if they meet NIH policy requirements and are appropriate to the project.
What is the listed award ceiling for this opportunity?
The posted administrative details list an award ceiling of $600,000.
What is the grant type noted in the administrative details?
The posted administrative details indicate this opportunity is a discretionary grant.
What is the original closing date shown?
The original closing date shown in the posted details is 2023-03-15.
What is the record creation date shown?
The record creation date shown is 2022-12-16.
What is the central evidence-building goal of this research?
The central idea is to build a stronger, practice-ready evidence base for prevention programs that can be delivered in child welfare settings or accessed via child welfare referrals, producing actionable evidence about what works for opioid-related prevention outcomes in these populations.
Browse more opportunities from the same category: Education, Health
Next opportunity: Pediatric Heart Network Clinical Research Centers (UM1 Clinical Trial Optional)
Previous opportunity: FY 2022 COPS Technology and Equipment Program Invitational Solicitation II
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA DA 24 012
Applicants also applied for:
Applicants who have applied for this opportunity (RFA DA 24 012) also looked into and applied for these:
| Funding Opportunity |
|---|
| Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21 Clinical Trial Optional) Apply for RFA CA 23 014 Funding Number: RFA CA 23 014 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) Apply for RFA CA 23 016 Funding Number: RFA CA 23 016 Agency: National Institutes of Health Category: Education, Health Funding Amount: $600,000 |
| Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional) Apply for RFA CA 23 015 Funding Number: RFA CA 23 015 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) Apply for RFA CA 23 017 Funding Number: RFA CA 23 017 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Translational Centers for Microphysiological Systems (TraCe MPS) (U2C Clinical Trials Not Allowed) Apply for RFA TR 23 001 Funding Number: RFA TR 23 001 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NIDA Core "Center of Excellence" Grant Program (P30 Clinical Trial Optional) Apply for PAR 23 049 Funding Number: PAR 23 049 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed) Apply for PAR 23 088 Funding Number: PAR 23 088 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| NIDA Program Project Grant Applications (P01 Clinical Trial Optional) Apply for PAR 23 064 Funding Number: PAR 23 064 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NIDA Research Center of Excellence Grant Program (P50 Clinical Trial Optional) Apply for PAR 23 076 Funding Number: PAR 23 076 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Career Enhancement Award to Advance Research on Firearm Injury and Mortality Prevention (K18 Independent Clinical Trial Required) Apply for PAR 23 107 Funding Number: PAR 23 107 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Career Enhancement Award to Advance Research on Firearm Injury and Mortality Prevention (K18 Independent Clinical Trial Not Allowed) Apply for PAR 23 108 Funding Number: PAR 23 108 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional) Apply for RFA DA 24 037 Funding Number: RFA DA 24 037 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Education Activities for Responsible Analyses of Complex, Large-Scale Data (R25- Clinical Trial Not Allowed) Apply for RFA DA 24 027 Funding Number: RFA DA 24 027 Agency: National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R21 Clinical Trials Not Allowed) Apply for RFA DA 24 009 Funding Number: RFA DA 24 009 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
| Leveraging Big Data Science to Elucidate the Mechanisms of HIV Activity and Interaction with Substance Use Disorder (R01 Clinical Trials Not Allowed) Apply for RFA DA 24 008 Funding Number: RFA DA 24 008 Agency: National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Advancing Integrated Models (AIM) of Care to Improve Pregnancy Outcomes among Women Who Experience Persistent Disparities (R01 Clinical Trial Optional) Apply for RFA NR 23 002 Funding Number: RFA NR 23 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Evaluating the Impact of Pandemic Era related Food and Housing Policies and Programs on Health Outcomes in Health Disparity Populations (R01 Clinical Trial Optional) Apply for RFA NR 23 003 Funding Number: RFA NR 23 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Clinical-Community Linkages to Address Social Needs and Social Conditions to Advance Health Equity among Populations Experiencing Health Disparities: The Bridge-to-Care Initiative (R01 Clinical Trial Required) Apply for RFA NR 23 004 Funding Number: RFA NR 23 004 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed) Apply for RFA DA 24 001 Funding Number: RFA DA 24 001 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Genomic Community Resources (U24 Clinical Trial Not Allowed) Apply for PAR 23 124 Funding Number: PAR 23 124 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA DA 24 012", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.