Opportunity Information: Apply for HT9425 23 PRMRP DA
The Department of Defense (DoD), through the U.S. Army Medical Research Acquisition Activity (USAMRAA), offered the Peer Reviewed Medical Research Program (PRMRP) Discovery Award (Funding Opportunity Number: HT9425 23 PRMRP DA). This opportunity sits in the science and technology and broader research and development category (CFDA 12.420) and is intended to fund early, concept-driven work rather than incremental extensions of existing projects. The core purpose is to back innovative, high-risk research that has the potential for high reward by generating genuinely new insights, shifting current scientific paradigms, or creating new technologies or applications. In practical terms, the program is looking for studies that can open up new directions for future research rather than simply filling small gaps in what is already known.
A central expectation of the Discovery Award is that proposed projects are grounded in a clear and testable hypothesis. The announcement emphasizes that the hypothesis should be supported by a sound scientific rationale and a well-constructed study design, which signals that novelty alone is not enough; applicants need to show that the work is thoughtfully planned and that the approach is capable of producing interpretable results. At the same time, the award is explicitly positioned to encourage non-incremental ideas, meaning it is aimed at bold or unconventional concepts that could materially change how a problem is understood or addressed if successful.
In terms of what research activities are allowed, the mechanism cannot be used to conduct clinical trials. However, it does allow non-interventional clinical research studies, which generally means studies where researchers do not assign participants to receive specific interventions as part of the protocol. That can include certain observational or correlational human studies, data or specimen analyses, and other clinical research approaches that do not meet the definition of a clinical trial. This boundary is important for applicants to consider when shaping project aims and methods, especially for proposals involving human subjects or clinical settings.
The opportunity was listed as discretionary funding and could be supported through either a grant or a cooperative agreement, depending on the structure of the award and the expected level of involvement by the funding agency. Eligibility was described as unrestricted, meaning it was broadly open to many entity types, subject to any additional eligibility clarifications contained in the full announcement. The posting date for the opportunity was January 31, 2023, and the original application closing date was April 26, 2023. The listing also projected approximately 60 expected awards, suggesting a relatively substantial portfolio of funded projects for that cycle. The stated award ceiling in the provided source data is shown as 0, which typically indicates that the ceiling was not specified in that field of the summary record and would normally need to be confirmed in the full solicitation or program announcement details.
Overall, this funding opportunity is best understood as a DoD medical research seed-and-launch style mechanism: it prioritizes creativity and potential impact, requires a rigorous hypothesis-driven plan, supports foundational work that can catalyze future studies, and draws a firm line against interventional clinical trials while still allowing certain types of non-interventional clinical research.Apply for HT9425 23 PRMRP DA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Medical, Discovery Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Jan 31, 2023.
- Applicants must submit their applications by Apr 26, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 60 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Peer Reviewed Medical Research Program (PRMRP) Discovery Award - FAQs
What is the name of this funding opportunity?
This opportunity is the Peer Reviewed Medical Research Program (PRMRP) Discovery Award, Funding Opportunity Number HT9425 23 PRMRP DA.
Which agency is offering the Discovery Award?
The Department of Defense (DoD) is offering the opportunity through the U.S. Army Medical Research Acquisition Activity (USAMRAA).
What category does this opportunity fall under?
The opportunity is in the science and technology and broader research and development category and is associated with CFDA 12.420.
What is the main goal of the PRMRP Discovery Award?
The main goal is to fund early, concept-driven research that is innovative and high-risk but has the potential for high reward. The program emphasizes work that can generate genuinely new insights, shift scientific paradigms, or create new technologies or applications.
What kind of projects is the Discovery Award designed to support?
It is designed to support bold, non-incremental ideas that can open new directions for future research. The intent is not to fund small extensions of existing work, but to support concepts that could materially change how a problem is understood or addressed if successful.
Is incremental research considered a good fit for this mechanism?
Based on the description provided, the Discovery Award is positioned to encourage non-incremental research rather than incremental extensions of existing projects.
Does the Discovery Award require a specific scientific structure, like a hypothesis?
Yes. A central expectation is that the proposed project is grounded in a clear and testable hypothesis supported by sound scientific rationale.
How important are study design and rigor for this award?
They are emphasized as important. The announcement highlights the need for a well-constructed study design, indicating that novelty alone is not enough and the approach should be capable of producing interpretable results.
Are clinical trials allowed under this award?
No. The mechanism cannot be used to conduct clinical trials.
What types of human or clinical research are allowed if clinical trials are not permitted?
Non-interventional clinical research studies are allowed. This generally includes research where investigators do not assign participants to receive specific interventions as part of the protocol. Examples described include certain observational or correlational human studies and data or specimen analyses, as long as the work does not meet the definition of a clinical trial.
Why does the clinical trial restriction matter when planning a proposal?
It affects how project aims and methods should be shaped, especially for proposals involving human subjects or clinical settings. Applicants need to ensure the planned work does not cross into an interventional clinical trial design.
What funding instrument will be used (grant vs. cooperative agreement)?
The opportunity could be supported through either a grant or a cooperative agreement, depending on the structure of the award and the expected level of involvement by the funding agency.
What does it mean that the opportunity is listed as discretionary funding?
It indicates the funding is offered as discretionary (as described in the provided summary), rather than being a mandatory entitlement-type program.
Who is eligible to apply?
Eligibility was described as unrestricted, meaning it was broadly open to many entity types, subject to any additional eligibility clarifications in the full announcement.
When was this opportunity posted?
The posting date listed for the opportunity is January 31, 2023.
What was the application closing date?
The original application closing date was April 26, 2023.
How many awards were expected to be made?
The listing projected approximately 60 expected awards for that cycle.
What is the maximum award amount (award ceiling)?
The award ceiling is shown as 0 in the provided source data. In many summary records, this typically means the ceiling was not specified in that particular field and would usually need to be confirmed in the full solicitation or program announcement.
How should applicants interpret the "award ceiling = 0" notation?
Based on the information provided, it should be treated as an unspecified ceiling in the summary record rather than a literal $0 maximum, and the actual ceiling would normally be confirmed in the full announcement.
What is the overall "fit" of this award for an idea-stage project?
It is described as a seed-and-launch style mechanism: it prioritizes creativity and potential impact, expects a rigorous hypothesis-driven plan, supports foundational work that can catalyze future studies, and prohibits interventional clinical trials while allowing certain non-interventional clinical research.
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| DoD Peer Reviewed Medical, Clinical Trial Award Apply for HT9425 23 PRMRP CTA Funding Number: HT9425 23 PRMRP CTA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical, Focused Program Award Apply for HT9425 23 PRMRP FPA Funding Number: HT9425 23 PRMRP FPA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical, Investigator-Initiated Research Award Apply for HT9425 23 PRMRP IIRA Funding Number: HT9425 23 PRMRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical, Technology Therapeutic Development Award Apply for HT9425 23 PRMRP TTDA Funding Number: HT9425 23 PRMRP TTDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical, Lifestyle and Behavioral Health Interventions Research Award Apply for HT9425 23 PRMRP LBIRA Funding Number: HT9425 23 PRMRP LBIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DOD Epilepsy, Research Partnership Award Apply for HT9425 23 ERP RPA Funding Number: HT9425 23 ERP RPA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Epilepsy, Virtual Post-Traumatic Epilepsy Research Center Faculty Award Apply for HT9425 23 ERP VIRTUAL P TERC F Funding Number: HT9425 23 ERP VIRTUAL P TERC F Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Breast Cancer, Breakthrough Award Levels 1 and 2 Apply for HT9425 23 BCRP BTA12 Funding Number: HT9425 23 BCRP BTA12 Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Breast Cancer, Clinical Research Extension Award Apply for HT9425 23 BCRP CREA2 Funding Number: HT9425 23 BCRP CREA2 Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Breast Cancer, Breakthrough Award Level 3 Apply for HT9425 23 BCRP BTA3 Funding Number: HT9425 23 BCRP BTA3 Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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